Sex Hormone Binding Globulin (SHBG)

  • ISI Order Code:

    SHBG

  • CPT Code:

    84270

Clinical Significance:

Procedure:

Serotonin is measured by direct ELISA.

SHBG (Sex Hormone-binding Globulin) is a variably glycosylated, secreted, non-disulfide-linked homodimer. In circulation, SHBG binds to male and female sex hormones with equal affinity. It plays a role in regulating hormone access to target tissues and controlling the availability (“free”) of active hormones in circulation.

Reference Range:

Female             8 – 158 nmol/L
Male                10 – 99 nmol/L

Expected Turn-around-Time:

 7-10 Business Days

Turnaround time is defined as the usual number of days from the date of receipt of a specimen for testing to when the result is released to the ordering facility.

Patient Preparation:

Patient should not be on any Steroid, ACTH, Gonadotropin or Estrogen medications, if possible, for at least 48 hours prior to collection of specimen. 

Specimen Collection:

3 ml serum or EDTA plasma should be collected and separated as soon as possible.  Minimum specimen size is 0.5 ml.

Special Specimens:

For tumor/tissue and various fluids (i.e. CSF, peritoneal, synovial, etc.) contact the Institute for requirements and special handling.

Shipping Instructions:

Ship specimens frozen in dry ice.

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