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Traditional biomarkers such as chromogranin A (CgA) and 5-HIAA remain important in neuroendocrine tumor (NET) care. However, recent research shows that inflammation within the tumor microenvironment plays a major role...

Introduction Diabesity—the intersection of obesity and type 2 diabetes—is typically described as a metabolic disorder. However, growing evidence now shows that immune imbalance, particularly involving mast cells, plays a significant...

The term “diabesity” reflects the increasingly inseparable relationship between obesity and type 2 diabetes—a dual epidemic driving metabolic dysfunction, cardiovascular disease, and rising healthcare costs worldwide. As prevalence continues to...

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Neuroendocrine Tumor (NETs)

Traditional biomarkers such as chromogranin A (CgA) and 5-HIAA remain important in neuroendocrine tumor (NET) care. However, recent research shows that inflammation within the tumor...

5-Hydroxyindoleacetic acid (5-HIAA) is the primary metabolite of serotonin and is a critical biomarker in the diagnosis and monitoring of serotonin-secreting neuroendocrine tumors (NETs), including...

Immunohistochemistry remains the go-to method in clinical settings for diagnosing neuroendocrine tumors (NETs), even over newer, state-of-the-art techniques such as next-generation sequencing (NGS). It is...

Diabesity

Introduction Diabesity—the intersection of obesity and type 2 diabetes—is typically described as a metabolic disorder. However, growing evidence now shows that immune imbalance, particularly involving...

The term “diabesity” reflects the increasingly inseparable relationship between obesity and type 2 diabetes—a dual epidemic driving metabolic dysfunction, cardiovascular disease, and rising healthcare costs...

When it comes to managing conditions like diabetes and obesity, most people think about diet, exercise, and medication. But behind the scenes, certain hormones in...

Inflammation Markers

Prostaglandins and chemokines are powerful signaling molecules that influence inflammation, immune responses, and tissue function. Among these, Prostaglandin D₂ (PGD₂), Prostaglandin F₂α (PGF₂α), Prostaglandin E₂...

Inflammation is associated with many processes such as cancer, infection, diet or even just reactive ones (e.g. sports injuries). In fact, even the recent COVID...

Other

For a long time, it was believed that the primary role of peptides produced by proteasomes was to help T cells in the immune system...

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Neuroendocrine Tumor (NETs)

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